The U.S. President’s Emergency Plan for AIDS Relief (PEPFAR)

The American people, through the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), support the fight against global AIDS through bilateral and regional programs in 65 countries. PEPFAR is the largest commitment by any nation to address a single disease in history. Through PEPFAR, the U.S. Government has invested $70 billion dollars in bilateral HIV/AIDS programs, the Global Fund, and tuberculosis programs. In partnership with countries and other organizations, PEPFAR has helped reduce AIDS-related deaths by 45 percent since their peak in 2004.

As of September 2015, PEPFAR global investments have resulted in:

  • 5 million men, women, and children on life-saving antiretroviral treatments.
  • 9 million voluntary medical male circumcisions, preventing infections.
  • More than 1.5 million babies born HIV-free who would have otherwise been infected.
  • 5 million orphans and vulnerable children who receive care.
  • 190,000 new health care workers trained.


More than 1.5 million Ugandans are estimated to be living with HIV and AIDS. Since 2004, PEPFAR has collaborated with the Government of Uganda, national, international, and civil society organizations on building Uganda’s capacity to lead the HIV/AIDS response. Focus areas include care and treatment, prevention, impact mitigation, and health systems strengthening. Supported programs aim to achieve epidemic control by focusing on high impact, efficient interventions within populations and areas with elevated HIV prevalence rates. PEPFAR Uganda implements its programs through the U.S. Agency for International Development (USAID), U.S. Centers for Disease Control (CDC), U.S. Department of Defense, U.S. Department of State, and Peace Corps.

With PEPFAR’s support, Uganda is on course to achieve UNAID’s ambitious 90-90-90 goals (90 percent of people diagnosed, 90 percent of those diagnosed on ART, and 90 percent of those on ART virally suppressed) by 2020.

PEPFAR Uganda highlights:

  • The U.S. has invested $3 billion in PEPFAR Uganda since 2004.
  • 742,000 HIV-positive Ugandans are receiving lifelong ARV therapy.
  • 6 million pregnant women were tested for HIV last year.
  • 466,000 men were circumcised for HIV prevention last year.
  • The HIV positivity rate among exposed babies tested has decreased from 12 percent in 2010 to 5.3 percent in 2015 through Prevention of Mother-to-Child Transmission activities.